Molecular mechanisms of normal iron homeostasis
نویسندگان
چکیده
منابع مشابه
Molecular mechanisms of normal iron homeostasis.
Humans possess elegant control mechanisms to maintain iron homeostasis by coordinately regulating iron absorption, iron recycling, and mobilization of stored iron. Dietary iron absorption is regulated locally by hypoxia inducible factor (HIF) signaling and iron-regulatory proteins (IRPs) in enterocytes and systematically by hepatic hepcidin, the central iron regulatory hormone. Hepcidin not onl...
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ژورنال
عنوان ژورنال: Hematology
سال: 2009
ISSN: 1520-4391,1520-4383
DOI: 10.1182/asheducation-2009.1.207